Making thrombolysis safer in stroke

Thrombolysis in Stroke Patients; Problems and Limitations

Thrombolysis for stroke is being used in some developing countries. This study was designed to evaluate the problems of thrombolysis therapy in Iran. During January-July 2008, all patients with ischemic stroke admitted to Ghaem Hospital, Mashhad, northeast Iran, were enrolled in a prospective observational study. Ghaem Hospital is a tertiary care hospital that includes infrastructure for thromb...

Perfusion computed tomography to assist decision making for stroke thrombolysis

The use of perfusion imaging to guide selection of patients for stroke thrombolysis remains controversial because of lack of supportive phase three clinical trial evidence. We aimed to measure the outcomes for patients treated with intravenous recombinant tissue plasminogen activator (rtPA) at a comprehensive stroke care facility where perfusion computed tomography was routinely used for thromb...

Making Electronic Refunds Safer

We show how to break an electronic cash protocol due to van Antwerpen (a refinement of the system proposed by Chaum, Fiat, and Naor), and give an alternative protocol that fixes the problem.

Making carotid surgery safer.

Carotid surgery has been shown to be beneficial in level one randomised trials. However, evidence suggests that current outcomes do not match those published in 1991. In order to make carotid endarterectomy safer in the future, it is essential to optimise patient selection and risk factor management and to maintain an obsessional approach to surgical technique. A planned strategy of monitoring ...

Making safer treatment choices